API Donepezil HCl CAS 120011-70-3 Rau Alzheimer's Disease

Lus piav qhia luv luv:

Donepezil Hydrochloride yog hydrochloride ntsev ntawm piperidine derivative nrog neurocognitive-txhim kho kev ua si.Donepezil reversibly inhibits acetylcholinesterase, yog li thaiv cov hydrolysis ntawm neurotransmitter acetylcholine thiab, yog li ntawd, nce nws cov haujlwm.

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Product Detail

Khoom cim npe

Kev piav qhia

Donepezil yog siv los kho qhov tsis meej pem txog Alzheimer's kab mob.

Specification:

Khoom npe	Donepezil Hydrochloride
Tshuaj npe	1h-inden-1-ib, 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl) kuv
Lwm Lub Npe	Donepezil hcl;Donezepilhydrochloride;DonepezilHydrochloride (200mg); 2-((1-Benzylpiperidin-4-yl)Methyl)-5,6-diMethoxy-2,3-dihydro-1H-inden-1-onehydrochloride; 2,3-Dihydro -5,6-diMetChemicalbookhoxy-2-[[1-(phenylMethyl)-4-piperidinyl]Methyl]-;2-(1-Benzyl-4-piperidylmethyl)-5,6-dimethoxy-1-indanoneHydrochloride;Donepezil(Aricept) DonpezilHydrochlorideForMⅠ
CAS Nr	120011-70-3
Molecular Formula	C24H30ClNO3
Formula hnyav	415.95 ib
Qhov tshwm sim	Dawb mus rau dawb dawb crystalline khoom
Assay	98.0% min
Melting Point	220-222 ° C
Boiling Point	527.9 C ntawm 760 MmHg
Pob	20kg / hnab / nruas, 25kg / hnab / nruas, lossis raws li koj xav tau
Cia	Khaws lub thawv kaw kom nruj rau hauv qhov chaw qhuav thiab txias.Tsis txhob raug tshav ntuj ncaj qha.
COA & MSDS	Muaj
Daim ntawv thov	Rau kev tshawb fawb

Certificate of Analysis/COA:

TEST NTAWV	SPECIFICATION	TSEEM CEEB
Qhov tshwm sim	Tawm dawb mus rau dawb crystalline hmoov	Ua raws
Solubility	Dawb soluble hauv chloroform, soluble hauv dej thiab acetic acid, me ntsis soluble hauv Acetonitrile thiab ethanol, insoluble hauv Ethylacetoacetate thiab n-hexane.	Ua raws
Kev txheeb xyuas	(1) Los ntawm IR nqus, kom phim nrog cov qauv ua haujlwm.	Ua raws
	(2) Lub sijhawm khaws cia ntawm lub ncov loj ntawm cov qauv yuav tsum ua raws li cov qauv ua haujlwm.	Ua raws
	(3) Kev kuaj tshuaj chlorides.Teb rau qhov ntsuas rau Chlorides.	Ua raws
Dej	≤ 0.4%	0.31%
Residue ntawm ignition	≤0.1%	0.02%
Muaj feem xyuam	Desbenzyl dopezl: xyuas^a≤ 0.15% Donepezil pyridine analogue^b≤ 0.15% Donepezilzilbenzyl bromide hmoov^c≤ 0.15% Tom ntej: Dehydrodeoxy donepezil^d≤ 0.15% Deoxy ua tiav^e≤ 0.15% Ib qho Unkonwn ib qho impurity≤0.10% Tag nrho ≤0.5%	Tsis pom Tsis pom 0.02% Tsis pom Tsis pom 0.05% 0.18%
Hnyav hlau	≤ 20ppm	≤ 20ppm
Residual Solvents	Methanol ≤ 0.3%Ethanol ≤ 0.5%Ethyl acetate ≤0.5% Toluene ≤ 0.089% Acetic acid ≤ 0.5%	Tsis pom Tsis pom Tsis pom Tsis pom Tsis pom
Assay	Hauv paus qhuav, C₂₄H₂₉NO₃· HCl yuav tsum yog 98.0% rau 102.0%.	99.52%