API Obeticholic acid CAS 459789-99-2 rau biliary cholangitis

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Obeticholic acid yog siv ib leeg lossis hauv kev kho mob ua ke rau qee yam kab mob siab (thawj biliary cholangitis-PBC).

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Product Detail

Khoom cim npe

Kev piav qhia

Obeticholic acid yog siv ib leeg lossis hauv kev kho mob ua ke rau qee yam kab mob siab (thawj biliary cholangitis-PBC).

Specification:

Khoom npe	Obeticholic Acid
Tshuaj npe	6-Ethylchenodeoxycholic acid
Lwm Lub Npe	3A, 7A -DIHYDROXY-6A -ETHYL-5B-CHOLAN-24-OIC ACID; Obeticholic acid 6-ECDCA; 6alpha-Ethyl-chenodeoxycholic acid; 6-Ecdca; 6-Ethylchenodeoxycholic acid; 6alph; Obeticholic Acid 67, - ECDCA)
CAS Nr	459789-99-2
Molecular Formula	C26H44O4
Formula hnyav	420.63 ib
Qhov tshwm sim	Dawb hmoov
Assay	99.0% min
Qhov ntom	1.091 g / cm3
Melting Point	108-110 ° C
Boiling Point	562.9 ± 25.0 ° C
Pob	20kg / hnab / nruas, 25kg / hnab / nruas, lossis raws li koj xav tau
Cia	Khaws lub thawv kaw kom nruj rau hauv qhov chaw qhuav thiab txias.Tsis txhob raug tshav ntuj ncaj qha.
COA & MSDS	Muaj

Kev siv

Obeticholic acid yog dihydroxy-5beta-cholanic acid uas yog chenodeoxycholic acid nqa ib qho ntxiv ethyl hloov ntawm 6alpha-txoj hauj lwm.Ib tug semi-synthetic bile acid uas ua raws li ib tug farnesoid X receptor agonist thiab yog siv rau kev kho mob ntawm thawj biliary cholangitis.Nws muaj lub luag haujlwm ua farnesoid X receptor agonist thiab tus neeg saib xyuas hepatoprotective.Nws yog dihydroxy-5beta-cholanic acid, 3alpha-hydroxy steroid thiab 7alpha-hydroxy steroid.Nws muab los ntawm chenodeoxycholic acid.
Obeticholic acid (OCA) yog ib qho kev hloov kho cov kua tsib kua qaub thiab muaj zog agonist ntawm farnesoid X nuclear receptor (FXR) uas yog siv los kho cov kab mob siab nrog rau cov kab mob biliary cholangitis.