Pregabalin yog cov tshuaj tiv thaiv kab mob tshiab, muaj γ-amino butyric acid qauv ntawm nws cov qauv molecular, uas muaj cov tshuaj tiv thaiv kab mob.
Khoom Lub Npe | Pregabalin |
CAS Nr. | 148553-50-8 |
Kev dawb huv | 99% |
Cov Qauv Molecular | C8H17NO2 |
Molecular phaus | 159.23 |
Melting point | 194-196 ° C. |
Ceev | 0.997 ± 0.06 g/cm3 (Kwv yees) |
Tshwm sim | Dawb siv lead ua hmoov |
Qib | Qib tshuaj |
Qeb | Cov Khoom Siv Tshuaj Kho Mob (API) |
Chav Kawm Tshuaj | Anticonvulsant - GABA Analogs · Diabetic Peripheral Neuropathy Agents · Fibromyalgia Agents - GABA Analogs · Neuropathic Pain Therapy · Postherpetic Neuralgia Agents |
Hom | SHXLCHEM |
Nqe lus piav qhia | Dawb kom tawm dawb crystalline hmoov |
Indentification xim cov tshuaj tiv thaiv | Ninhydrin cov tshuaj tiv thaiv yog xiav ntshav |
Indentification los ntawm IR | IR spectrum zoo ib yam nrog tus qauv siv |
Solubility | Sparingily soluble hauv dej zoo |
Kev kho qhov muag tshwj xeeb | Nruab nrab ntawm +8.5 ° txog +12.0 ° |
Cov khoom muaj feem cuam tshuam los ntawm HPLC (-) Amide | Tsis ntau tshaj 0.15% |
4E | Tsis ntau tshaj 0.15% |
5E | Tsis ntau tshaj 0.15% |
Lactum | Tsis ntau tshaj 0.15% |
Tsis paub impurity | Tsis ntau tshaj 0.15% |
Tag nrho cov tsis huv | Tsis ntau tshaj 0.15% |
Hnyav hlau | Tsis pub ntau tshaj 200ppm |
Sulphated tshauv | Tsis ntau tshaj 0.1% w/w |
Poob ntawm ziab | Tsis ntau tshaj 0.5% w/w |
Methanol | Tsis ntau tshaj 3000ppm |
Toluene | Tsis ntau tshaj 890ppm |
N-butanol hmoov | Tsis ntau tshaj 5000ppm |
Ethyl acetate hmoov | Tsis ntau tshaj 5000ppm |
Chloroform | Tsis pub ntau tshaj 60ppm |
N-hexane tshuaj | Tsis ntau tshaj 290ppm |
Emantiomeric purity los ntawm HPLC R-Pregabalin cov ntsiab lus | Tsis ntau dua 0.15% ntawm thaj chaw R-Pregabalin |
Kev Ntsuas los ntawm HPLC (ntawm cov hauv paus qhuav) | Tsis ntau tshaj 98.0 w/w thiab Tsis ntau tshaj 102.0% w/w |
Pregabalin yog Cov Khoom Siv Tshuaj Kho Mob (API), feem ntau yog siv los tua qhov mob tshwm sim los ntawm kev puas tsuaj ntawm cov hlab ntshav vim ntshav qab zib, kab mob shingles (herpes zoster), lossis raug mob txha nraub qaum. Pregabalin kuj tseem siv los kho qhov mob hauv cov neeg mob fibromyalgia. Nws kuj tseem siv nrog lwm cov tshuaj los kho qee yam qaug dab peg (qaug dab peg).
Kuv yuav tsum noj tshuaj pregabalin li cas?
Hu rau: erica@shxlchem.com
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Lub sij hawm ua
≤25kg: tsis pub dhau peb hnub ua haujlwm tom qab tau txais kev them nyiaj.
>25kg: ib lub lim tiam
Qauv
Muaj
Pob
1kg ib lub hnab, 25kg rau ib lub nruas, lossis raws li koj xav tau.
Cia
Khaws lub thawv kaw nruj nreem hauv qhov chaw qhuav, txias thiab qhov cua zoo. Khaws sib nrug ntawm cov ntim khoom noj lossis cov khoom siv tsis sib xws.